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SCHERING AG
FSE: SCH  NYSE: SHR
Indice: DAX 30

Schering AG is a research-based pharmaceutical company. Its activities are focused on four business areas: Gynecology&Andrology, Diagnostics&Radiopharmaceuticals, Dermatology as well as Specialized Therapeutics for disabling diseases in the fields of the central nervous system, oncology and cardiovascular system. As a global player with innovative products Schering AG aims for leading positions in specialized markets worldwide. With in-house R&D and supported by an excellent global network of external partners, Schering AG is securing a promising product pipeline. Using new ideas, Schering AG aims to make a recognized contribution to medical progress and strives to improve the quality of life: making medicine work

Schering est un des acteurs majeurs de l'industrie pharmaceutique. 
- contraception et traitement hormonal  : contraceptif par voie orale (Diane, Mycrogynon), produits de traitement hormonal (patchs Climara, Mirena), traitement de la ménopause (Climen), traitement de l'endométrite (Endometrion)
- médicaments  : traitement de la sclérose (Betaferon/Betaseron), de la leucémie (Fludara), du cancer de la prostate (Androcur) et des problèmes cardiovasculaires (Betapace)
- produits de diagnostic : produits pour la radiologie classique (Iopamiron, Ultravist), pour l'IRM (n°1 mondial ; Magnevist) et pour la radiologie par ultrasons (Levovist)
- dermatologie  : traitement des maladies de la peau (Nerisona), corticoïdes pour l'eczéma (Advantan), produits contre l'acné (Skinoren)



Oral formulation of Fludara® approved in Japan
Berlin - Bayer Schering Pharma AG announced today that the oral formulation of 
Fludara® for low-grade non-Hodgkin’s Lymphoma and mantle cell lymphoma has received marketing approval in Japan. This new formulation provides a new avenue for simpler and easier outpatient chemotherapy to improve patients’ quality of life, as well as that of their families. Bayer Schering Pharma plans to start marketing of Fludara® Oral after National Healthcare Insurance price listing. 
"With the approval of Fludara® Oral in Japan, we are right on track to further expand our leadership position in hematological oncology," said Paolo Pucci, Head of the Oncology Business Unit at Bayer Schering Pharma. "The addition of Fludara® Oral to our portfolio will strengthen our position in Japan, the world’s second largest pharmaceutical market."

Interim Report Q1-3/2006
Q1-3/2006 at a Glance
NET SALES GROWTH: +7%
OPERATING PROFIT: +20% (adjusted)
BETAFERON®: +16%
In the first nine months of 2006, the Schering AG Group achieved an organic net sales growth of 9%.
Negative structure effects slightly impacted net sales growth. In total, net sales increased by 7% to €4,180m in comparison to the previous year’s figures. In the third quarter of 2006, total net sales remained at the previous year’s level. After adjusting for structure and negative currency effects, net sales increased by 5%. The recall of our X-ray contrast agent Ultravist® in the formulation 370 mgI/ml
had a negative impact on net sales. After adjusting for this effect, net sales increased by 7% in the third quarter 2006.
The operating profit during the first nine months of 2006 was €690m, 3% below the previous year’s result. After adjusting for one-time effects amounting to €163m in connection with divestitures and takeover-related expenses, the operating profit increased by 20% to €853m. Including these one-time effects, net profit (€466m) and earnings per share (€2.45) were each 3% below the previous year’s level.
Cash flows from operating activities amounted to €733m, 9% below the first nine months of 2005. OnSeptember 30, 2006, the net cash position (net of cash and cash equivalents, marketable securities and borrowings) was €1,311m in comparison to €954m at the end of 2005.
Key data €m Change €m Change
Q1-3/2006 Q1-3/2005 in % Q3/2006 Q3/2005 in %
Net sales 4,180 3,902 +7% 1,356 1,355 0%
Gross profit 3,219 2,972 +8% 1,044 1,036 +1%
Operating profit 690 710 –3% 280 244 +15%
Profit before taxes 734 751 –2% 291 248 +17%
Net profit 466 480 –3% 165 160 +3%
Cash flows from operating activities 733 805 –9% 199 385 –48%
Basic earnings per share (€) 2.45 2.53 –3% 0.87 0.85 +2%
Employees (Sept. 30, 2006 / Dec. 31, 2005) 23,050 24,124 –4% – – –
Top-selling products Net sales Q1-3/2006 Change from Q1-3/2005
€m total currency adjusted
1. Betaferon®/Betaseron® (Specialized Therapeutics) 727 +16% +16%
2. Yasmin®* (Gynecology&Andrology) 566 +34% +33%
3. Magnevist® (Diagnostic Imaging) 240 0% 0%
4. Mirena® (Gynecology&Andrology) 217 +28% +27%
5. Ultravist® (Diagnostic Imaging) 174 –8% –10%
6. Iopamiron® (Diagnostic Imaging) 160 –10% –5%
7. Diane® (Gynecology&Andrology) 134 +3% 0%
8. Microgynon® (Gynecology&Andrology) 110 +12% +10%
9. Meliane® (Gynecology&Andrology) 93 0% –2%
10. Fludara® (Oncology) 91 +16% +15%
Total 2,512 +13% +12%
Total as % of Group sales 60%
* Net sales include net sales of Yasmin®, YAZ® and Yasminelle®
In this Interim Report, percentage changes in our depiction of sales developments have been calculated on the basis of figures
expressed in thousands of euros.

Schering AG licenses SEGRA compound for ophthalmic use to Bausch & Lomb
Berlin, Germany, and Rochester, New York, USA
Schering AG, Germany (FSE: SCH; NYSE: SHR) and Bausch & Lomb (NYSE: BOL) announced today that Schering has granted an exclusive worldwide license to Bausch & Lomb to develop and market a selective glucocorticoid receptor agonist (SEGRA) for the non-systemic treatment of eye disorders.
Bausch & Lomb will evaluate the compound’s potential as a novel anti-inflammatory medication with an improved safety profile in ophthalmological indications. Today, glucocorticoids are the most potent and most frequently used anti-inflammatory compounds, but their value is limited by side effects such as glaucoma induction. SEGRAs, using a distinct molecular mechanism after binding to a glucocorticoid receptor, may demonstrate a superior effect/side effect profile when compared to standard glucocorticoids.
“The collaboration with Bausch & Lomb is an excellent opportunity for us to broadly explore the potential of SEGRAs and capitalize on the full value of these compounds,” said Dr. Khusru Asadullah, Head of Inflammation Research at Schering AG.

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